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1

Quaternary Ammonium Compounds: An Antimicrobial Mainstay and Platform for Innovation to Address Bacterial Resistance

Jennings, Megan C., Minbiole, Kevin P. C., Wuest, William M.

Journal:

ACS Infectious Diseases

Year:

2015

Language:

english

File:

PDF, 3.12 MB

english, 2015

2

Short-term exposure to coal combustion waste has little impact on the skin microbiome of adult spring peepers, Pseudacris crucifer

Hughey, Myra C., Walke, Jenifer B., Becker, Matthew H., Umile, Thomas P., Burzynski, Elizabeth A., Minbiole, Kevin P.C., Iannetta, Anthony A., Santiago, Celina N., Hopkins, William A., Belden, Lisa K.

Journal:

Applied and Environmental Microbiology

Year:

2016

Language:

english

File:

PDF, 840 KB

english, 2016

3

Biofilm-Eradicating Properties of Quaternary Ammonium Amphiphiles: Simple Mimics of Antimicrobial Peptides

Jennings, Megan C., Ator, Laura E., Paniak, Thomas J., Minbiole, Kevin P. C., Wuest, William M.

Journal:

Year:

2014

Language:

english

File:

PDF, 1.06 MB

english, 2014

4

Total Synthesis of (+)-Phorboxazole A

Smith, Amos B., Verhoest, Patrick R., Minbiole, Kevin P., Schelhaas, Michael

Journal:

Journal of the American Chemical Society

Year:

2001

Language:

english

File:

PDF, 76 KB

english, 2001

5

Phylogenetic distribution of symbiotic bacteria from Panamanian amphibians that inhibit growth of the lethal fungal pathogen Batrachochytrium dendrobatidis

Becker, Matthew H., Walke, Jenifer B., Murrill, Lindsey, Woodhams, Douglas C., Reinert, Laura K., Rollins-Smith, Louise A., Burzynski, Elizabeth A., Umile, Thomas P., Minbiole, Kevin P. C., Belden, Li

Journal:

Molecular Ecology

Year:

2015

Language:

english

File:

PDF, 1001 KB

english, 2015

6

1,3-Dienes || Synthesis from Arenes and Polyenes

Rawal, V. H., Kozmin, S. A., Abell, A. D., Edmonds, M. K., Takeda, T., Tsubouchi, A., Diver, S. T., Minbiole, K. P. C., Gandon, V., Thorimbert, S., Malacria, M., Negishi, E., Wang, G., Shindo, M., Yos

Year:

2009

Language:

english

File:

PDF, 988 KB

english, 2009

7

1,3-Dienes || Synthesis by Isomerization of Unconjugated Dienes, Allenes, Alkynes, and Methylenecyclopropanes

Rawal, V. H., Kozmin, S. A., Abell, A. D., Edmonds, M. K., Takeda, T., Tsubouchi, A., Diver, S. T., Minbiole, K. P. C., Gandon, V., Thorimbert, S., Malacria, M., Negishi, E., Wang, G., Shindo, M., Yos

Year:

2009

Language:

english

File:

PDF, 793 KB

english, 2009

8

1,3-Dienes || Synthesis via Metal Complexes of Dienes

Rawal, V. H., Kozmin, S. A., Abell, A. D., Edmonds, M. K., Takeda, T., Tsubouchi, A., Diver, S. T., Minbiole, K. P. C., Gandon, V., Thorimbert, S., Malacria, M., Negishi, E., Wang, G., Shindo, M., Yos

Year:

2009

Language:

english

File:

PDF, 643 KB

english, 2009

9

Ester- and amide-containing multiQACs: Exploring multicationic soft antimicrobial agents

Allen, Ryan A., Jennings, Megan C., Mitchell, Myles A., Al-Khalifa, Saleh E., Wuest, William M., Minbiole, Kevin P.C.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2017

Language:

english

File:

PDF, 607 KB

english, 2017

10

Further Investigations into RigidityâActivity Relationships in BisQAC Amphiphilic Antiseptics

Leitgeb, Austin J., Feliciano, Javier A., Sanchez, Hugo A., Allen, Ryan A., Morrison, Kelly R., Sommers, Kyle J., Carden, Robert G., Wuest, William M., Minbiole, Kevin P. C.

Journal:

Year:

2020

File:

PDF, 1.59 MB

2020

11

Are Quaternary Ammonium Compounds, the Workhorse Disinfectants, Effective against Severe Acute Respiratory Syndrome-Coronavirus-2?

Schrank, Cassandra L., Minbiole, Kevin P. C., Wuest, William M.

Journal:

ACS Infectious Diseases

Year:

2020

File:

PDF, 1.12 MB

2020

12

ChemInform Abstract: Phorboxazole Synthetic Studies. Part 1. Construction of a C(3—19) Subtarget. Exploiting an Extension of the Petasis—Ferrier Rearrangement.

Amos B. Smith III, Patrick R. Verhoest, Kevin P. Minbiole, John L. Lim

Journal:

Year:

1999

File:

PDF, 28 KB

1999

13

ChemInform Abstract: Phorboxazole Synthetic Studies. Part 2. Construction of a C(20—28) Subtarget, a Further Extension of the Petasis—Ferrier Rearrangement.

Amos B. Smith III, Kevin P. Minbiole, Patrick R. Verhoest, Thomas J. Beauchamp

Journal:

Year:

1999

File:

PDF, 26 KB

1999

14

ChemInform Abstract: Total Synthesis of (+)-Phorboxazole A.

Amos B. Smith III, Patrick R. Verhoest, Kevin P. Minbiole, Michael Schelhaas

Journal:

Year:

2001

File:

PDF, 25 KB

2001

15

ChemInform Abstract: Facile Assembly of 2,4-Orthogonally-Functionalized Oxazoles: Useful Bidirectional Linchpins.

Amos B. Smith III, Kevin P. Minbiole, Scott Freeze

Journal:

Year:

2002

File:

PDF, 29 KB

2002

16

ChemInform Abstract: Total Synthesis of (+)-Phorboxazole A Exploiting the Petasis—Ferrier Rearrangement.

Amos B. Smith III, Kevin P. Minbiole, Patrick R. Verhoest, Michael Schelhaas

Journal:

Year:

2002

File:

PDF, 34 KB

2002

17

A Cyclopropane Fragmentation Approach to Heterocycle Assembly: A Convergent Synthesis of Oxepanes.

Kerry E. O'Neil, Seth V. Kingree, Kevin P. C. Minbiole

Journal:

Year:

2005

File:

PDF, 19 KB

2005

18

Economics of electron beam accelerator facilities: Concept vs actual

Paul R. Minbiole

Journal:

Radiation Physics and Chemistry

Year:

1995

Language:

english

File:

PDF, 498 KB

english, 1995

19

Design of a multi-purpose electron beam processing plant: concept vs. actual

Paul R. Minbiole, Paul A. Edgcomb

Journal:

International Journal of Radiation Applications and Instrumentation. Part C. Radiation Physics and Chemistry

Year:

1988

Language:

english

File:

PDF, 669 KB

english, 1988

20

The Identification of 2,4-diacetylphloroglucinol as an Antifungal Metabolite Produced by Cutaneous Bacteria of the SalamanderPlethodon cinereus

Robert M. Brucker, Cambria M. Baylor, Robert L. Walters, Antje Lauer, Reid N. Harris, Kevin P. C. Minbiole

Journal:

Journal of Chemical Ecology

Year:

2008

Language:

english

File:

PDF, 149 KB

english, 2008

21

Amphibian Chemical Defense: Antifungal Metabolites of the MicrosymbiontJanthinobacterium lividumon the SalamanderPlethodon cinereus

Robert M. Brucker, Reid N. Harris, Christian R. Schwantes, Thomas N. Gallaher, Devon C. Flaherty, Brianna A. Lam, Kevin P. C. Minbiole

Journal:

Journal of Chemical Ecology

Year:

2008

Language:

english

File:

PDF, 233 KB

english, 2008

22

Total Synthesis of (+)-Phorboxazole A Exploiting the Petasis−Ferrier Rearrangement

Smith, Amos B., Minbiole, Kevin P., Verhoest, Patrick R., Schelhaas, Michael

Journal:

Journal of the American Chemical Society

Year:

2001

Language:

english

File:

PDF, 282 KB

english, 2001

23

ChemInform Abstract: Synthesis of 1,3-Dienes by Aldol and Related Condensation Reactions

K. P. C. Minbiole

Journal:

Year:

2012

File:

PDF, 18 KB

2012

24

Towards a Better Understanding of the Use of Probiotics for Preventing Chytridiomycosis in Panamanian Golden Frogs

Matthew H. Becker, Reid N. Harris, Kevin P. C. Minbiole, Christian R. Schwantes, Louise A. Rollins-Smith, Laura K. Reinert, Robert M. Brucker, Rickie J. Domangue, Brian Gratwicke

Journal:

Year:

2011

Language:

english

File:

PDF, 246 KB

english, 2011

25

The antibacterial activity of 4,4′-bipyridinium amphiphiles with conventional, bicephalic and gemini architectures

Melissa C. Grenier, Robert W. Davis, Kelsey L. Wilson-Henjum, Jade E. LaDow, Jacob W. Black, Kevin L. Caran, Kyle Seifert, Kevin P.C. Minbiole

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 527 KB

english, 2012

26

Synergistic Inhibition of the Lethal Fungal PathogenBatrachochytrium dendrobatidis: The Combined Effect of Symbiotic Bacterial Metabolites and Antimicrobial Peptides of the FrogRana muscosa

Myers, Jillian M., Ramsey, Jeremy P., Blackman, Alison L., Nichols, A. Elizabeth, Minbiole, Kevin P. C., Harris, Reid N.

Journal:

Journal of Chemical Ecology

Year:

2012

Language:

english

File:

PDF, 290 KB

english, 2012

27

Mitigating amphibian chytridiomycosis with bioaugmentation: characteristics of effective probiotics and strategies for their selection and use

Bletz, Molly C., Loudon, Andrew H., Becker, Matthew H., Bell, Sara C., Woodhams, Douglas C., Minbiole, Kevin P. C., Harris, Reid N., Gaillard, Jean-Michel

Journal:

Ecology Letters

Year:

2013

Language:

english

File:

PDF, 728 KB

english, 2013

28

TMEDA-derived biscationic amphiphiles: An economical preparation of potent antibacterial agents

Black, Jacob W., Jennings, Megan C., Azarewicz, Julianne, Paniak, Thomas J., Grenier, Melissa C., Wuest, William M., Minbiole, Kevin P.C.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2014

Language:

english

File:

PDF, 433 KB

english, 2014

29

Beyond paraquats: Dialkyl 3,3′- and 3,4′-bipyridinium amphiphiles as antibacterial agents

Ator, Laura E., Jennings, Megan C., McGettigan, Amanda R., Paul, Jared J., Wuest, William M., Minbiole, Kevin P.C.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2014

Language:

english

File:

PDF, 624 KB

english, 2014

30

Phorboxazole Synthetic Studies. 2. Construction of a C(20−28) Subtarget, a Further Extension of the Petasis−Ferrier Rearrangement

Smith, Amos B., Minbiole, Kevin P., Verhoest, Patrick R., Beauchamp, Thomas J.

Journal:

Organic Letters

Year:

1999

Language:

english

File:

PDF, 76 KB

english, 1999

31

Gut of Red-backed Salamanders (Plethodon cinereus) May Serve as a Reservoir for an Antifungal Cutaneous Bacterium

Wiggins, Patrick J., Smith, Jacob M., Harris, Reid N., Minbiole, Kevin P. C.

Journal:

Journal of Herpetology

Year:

2011

Language:

english

File:

PDF, 260 KB

english, 2011

32

Phorboxazole Synthetic Studies. 1. Construction of a C(3−19) Subtarget Exploiting an Extension of the Petasis−Ferrier Rearrangement

Smith, Amos B., Verhoest, Patrick R., Minbiole, Kevin P., Lim, John J.

Journal:

Organic Letters

Year:

1999

Language:

english

File:

PDF, 79 KB

english, 1999

33

A Cyclopropane Fragmentation Approach to Heterocycle Assembly: A Convergent Synthesis of Oxepanes

O'Neil, Kerry E., Kingree, Seth V., Minbiole, Kevin P. C.

Journal:

Organic Letters

Year:

2005

Language:

english

File:

PDF, 74 KB

english, 2005

34

The Bacterially Produced Metabolite Violacein Is Associated with Survival of Amphibians Infected with a Lethal Fungus

Becker, M. H., Brucker, R. M., Schwantes, C. R., Harris, R. N., Minbiole, K. P. C.

Journal:

Applied and Environmental Microbiology

Year:

2009

Language:

english

File:

PDF, 172 KB

english, 2009

35

The antimicrobial activity of mono-, bis-, tris-, and tetracationic amphiphiles derived from simple polyamine platforms

Paniak, Thomas J., Jennings, Megan C., Shanahan, Paul C., Joyce, Maureen D., Santiago, Celina N., Wuest, William M., Minbiole, Kevin P.C.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2014

Language:

english

File:

PDF, 936 KB

english, 2014

36

Composition of symbiotic bacteria predicts survival in Panamanian golden frogs infected with a lethal fungus

Becker, M. H., Walke, J. B., Cikanek, S., Savage, A. E., Mattheus, N., Santiago, C. N., Minbiole, K. P. C., Harris, R. N., Belden, L. K., Gratwicke, B.

Journal:

Proceedings Biological Sciences

Year:

2015

Language:

english

File:

PDF, 546 KB

english, 2015

37

New sources of lycopsamine-type pyrrolizidine alkaloids and their distribution in Apocynaceae

Burzynski, Elizabeth A., Minbiole, Kevin P.C., Livshultz, Tatyana

Journal:

Biochemical Systematics and Ecology

Year:

2015

Language:

english

File:

PDF, 354 KB

english, 2015

38

The cutaneous bacterium Janthinobacterium lividum inhibits the growth of Trichophyton rubrum in vitro

Ramsey, Jeremy P., Mercurio, Albert, Holland, Jessica A., Harris, Reid N., Minbiole, Kevin P. C.

Journal:

International Journal of Dermatology

Year:

2015

Language:

english

File:

PDF, 128 KB

english, 2015

39

Bioorganic Investigation of Multicationic Antimicrobials to Combat QAC-Resistant Staphylococcus aureus

Jennings, Megan C., Buttaro, Bettina A., Minbiole, Kevin P. C., Wuest, William M.

Journal:

ACS Infectious Diseases

Year:

2015

Language:

english

File:

PDF, 4.38 MB

english, 2015

40

Interactions between amphibians' symbiotic bacteria cause the production of emergent anti-fungal metabolites

Loudon, Andrew H., Holland, Jessica A., Umile, Thomas P., Burzynski, Elizabeth A., Minbiole, Kevin P. C., Harris, Reid N.

Journal:

Frontiers in Microbiology

Year:

2014

Language:

english

File:

PDF, 1.21 MB

english, 2014

41

Immunomodulatory metabolites released by the frog-killing fungus, Batrachochytrium dendrobatidis

Rollins-Smith, Louise A., Fites, J. Scott, Reinert, Laura K., Shiakolas, Andrea R., Umile, Thomas P., Minbiole, Kevin P.C.

Journal:

Infection and Immunity

Year:

2015

Language:

english

File:

PDF, 588 KB

english, 2015

42

Facile Assembly of 2,4-Orthogonally-Functionalized Oxazoles: Useful Bidirectional Linchpins

Smith III., Amos B., Minbiole, Kevin P., Freeze, Scott

Journal:

Year:

2001

Language:

english

File:

PDF, 74 KB

english, 2001

43

The Evolution of an English Course

John Schmittroth, Craig Minbiole and Susan Cameron

Journal:

College Composition and Communication

Year:

1969

File:

PDF, 972 KB

1969

44

The Evolution of an English Course

John Schmittroth, Craig Minbiole and Susan Cameron

Journal:

College Composition and Communication

Year:

1969

Language:

english

File:

PDF, 972 KB

english, 1969

45

Gut of Red-backed Salamanders (Plethodon cinereus) May Serve as a Reservoir for an Antifungal Cutaneous Bacterium

Patrick J. Wiggins, Jacob M. Smith, Reid N. Harris and Kevin P. C. Minbiole

Journal:

Journal of Herpetology

Year:

2011

Language:

english

File:

PDF, 888 KB

english, 2011

46

Natural product-derived quaternary ammonium compounds with potent antimicrobial activity

Joyce, Maureen D, Jennings, Megan C, Santiago, Celina N, Fletcher, Madison H, Wuest, William M, Minbiole, Kevin PC

Journal:

The Journal of Antibiotics

Year:

2015

Language:

english

File:

PDF, 883 KB

english, 2015

47

The Petasis-Ferrier rearrangement: developments and applications

Minbiole, Emily C, Minbiole, Kevin P C

Journal:

The Journal of Antibiotics

Year:

2016

Language:

english

File:

PDF, 1.38 MB

english, 2016

48

From antimicrobial activity to mechanism of resistance: the multifaceted role of simple quaternary ammonium compounds in bacterial eradication

Minbiole, Kevin P.C., Jennings, Megan C., Ator, Laura E., Black, Jacob W., Grenier, Melissa C., LaDow, Jade E., Caran, Kevin L., Seifert, Kyle, Wuest, William M.

Journal:

Year:

2016

Language:

english

File:

PDF, 757 KB

english, 2016

49

Organic synthesis in the Smith Group: a personal selection of a dozen lessons learned at the University of Pennsylvania

Minbiole, Kevin P C

Journal:

The Journal of Antibiotics

Year:

2016

Language:

english

File:

PDF, 2.19 MB

english, 2016

50

Our Love Affair with Literature || Shane

Journal:

The English Journal

Year:

1999

Language:

english

File:

PDF, 160 KB

english, 1999